Anti-IRF2BP2 antibody (Internal) (STJ72492)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-IRF2BP2 (Internal) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 80kDa band in Mouse fetal Lung lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | IRF2BP2 |
| Gene ID | 359948 |
| Uniprot ID | I2BP2_HUMAN |
| Accession Number | NP_892017.2; NP_001070865.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QHGHSGPFESKFK |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_892017.2; NP_001070865.1). |
Additional Info
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner.this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation. |
| Protein Name | Interferon Regulatory Factor 2-Binding Protein 2Irf-2-Binding Protein 2Irf-2bp2 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Interferon Regulatory Factor 2-Binding Protein 2 antibodyAnti-Irf-2-Binding Protein 2 antibodyAnti-Irf-2bp2 antibodyAnti-IRF2BP2 antibody |
Information sourced from Uniprot.org