Anti-IP3KC antibody (Internal) (STJ71775)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-IP3KC (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx. 75kDa band observed in Human Pancreas, Heart and Skeletal Muscle lysates (calculated MW of 75.2kDa according to NP_079470.1). Recommended concentration: 1-3µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ITPKC |
| Gene ID | 80271 |
| Uniprot ID | IP3KC_HUMAN |
| Accession Number | NP_079470.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | ETERPKQKTEPDRSS |
Additional Info
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. |
| Protein Name | Inositol-Trisphosphate 3-Kinase CInositol 1 -4 -5-Trisphosphate 3-Kinase CIp3 3-Kinase CIp3k CInsp 3-Kinase C |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | NucleusCytoplasmShuttles Actively Between Nucleus And Cytoplasm With Both Nuclear Import And Nuclear Export Activity |
| Alternative Antibody Names | Anti-Inositol-Trisphosphate 3-Kinase C antibodyAnti-Inositol 1 -4 -5-Trisphosphate 3-Kinase C antibodyAnti-Ip3 3-Kinase C antibodyAnti-Ip3k C antibodyAnti-Insp 3-Kinase C antibodyAnti-ITPKC antibodyAnti-IP3KC antibody |
Information sourced from Uniprot.org