| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-IP3KC (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx. 75kDa band observed in Human Pancreas, Heart and Skeletal Muscle lysates (calculated MW of 75.2kDa according to NP_079470.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ITPKC |
| Gene ID: | 80271 |
| Uniprot ID: | IP3KC_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_079470.1 |
| Immunogen Sequence: | ETERPKQKTEPDRSS |
| Function | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis. Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. |
| Protein Name | Inositol-Trisphosphate 3-Kinase CInositol 1 -4 -5-Trisphosphate 3-Kinase CIp3 3-Kinase CIp3k CInsp 3-Kinase C |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | NucleusCytoplasmShuttles Actively Between Nucleus And Cytoplasm With Both Nuclear Import And Nuclear Export Activity |
| Alternative Antibody Names | Anti-Inositol-Trisphosphate 3-Kinase C antibodyAnti-Inositol 1 -4 -5-Trisphosphate 3-Kinase C antibodyAnti-Ip3 3-Kinase C antibodyAnti-Ip3k C antibodyAnti-Insp 3-Kinase C antibodyAnti-ITPKC antibodyAnti-IP3KC antibody |
Information sourced from Uniprot.org