Anti-INPP5K antibody (STJA0008284)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human INPP5K
General Information
| Short Description | Rabbit polyclonal anti-Inositol polyphosphate 5-phosphatase K for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | INPP5K |
| Gene ID | 51763 |
| Uniprot ID | INP5K_HUMAN |
| Immunogen | Synthesized peptide derived from human INPP5K |
| Specificity | This antibody detects endogenous levels of INPP5K at Human, Mouse |
Additional Info
| Function | Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases.therefore, is the specific regulator for insulin signaling in skeletal muscle. |
| Protein Name | Inositol Polyphosphate 5-Phosphatase KPhosphatidylinositol-3 -4 -5-Trisphosphate 5-PhosphatasePhosphatidylinositol-4 -5-Bisphosphate 5-PhosphataseSkeletal Muscle And Kidney-Enriched Inositol Phosphatase |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | Endoplasmic ReticulumCytoplasmFollowing Stimulation With EgfTranslocates To Membrane RufflesConcentrated At The Periphery Of The Nucleus |
| Alternative Antibody Names | Anti-Inositol Polyphosphate 5-Phosphatase K antibodyAnti-Phosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol-4 -5-Bisphosphate 5-Phosphatase antibodyAnti-Skeletal Muscle And Kidney-Enriched Inositol Phosphatase antibodyAnti-INPP5K antibodyAnti-PPS antibodyAnti-SKIP antibody |
Information sourced from Uniprot.org