| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Inositol polyphosphate 5-phosphatase K is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
INPP5K |
| Gene ID: |
51763 |
| Uniprot ID: |
INP5K_HUMAN |
| Specificity: |
This antibody detects endogenous levels of INPP5K at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human INPP5K |
| Function | Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate. Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases.therefore, is the specific regulator for insulin signaling in skeletal muscle. |
| Protein Name | Inositol Polyphosphate 5-Phosphatase KPhosphatidylinositol-3 -4 -5-Trisphosphate 5-PhosphatasePhosphatidylinositol-4 -5-Bisphosphate 5-PhosphataseSkeletal Muscle And Kidney-Enriched Inositol Phosphatase |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | Endoplasmic ReticulumCytoplasmFollowing Stimulation With EgfTranslocates To Membrane RufflesConcentrated At The Periphery Of The Nucleus |
| Alternative Antibody Names | Anti-Inositol Polyphosphate 5-Phosphatase K antibodyAnti-Phosphatidylinositol-3 -4 -5-Trisphosphate 5-Phosphatase antibodyAnti-Phosphatidylinositol-4 -5-Bisphosphate 5-Phosphatase antibodyAnti-Skeletal Muscle And Kidney-Enriched Inositol Phosphatase antibodyAnti-INPP5K antibodyAnti-PPS antibodyAnti-SKIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
