Anti-IMPA1/IMP1 antibody (1-277aa) [AT2G5] (STJA0041776)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human IMPA1 (1-277aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-IMPA1/IMP1 (1-277aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF/FACS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT2G5 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IMPA1 |
| Gene ID | 3612 |
| Uniprot ID | IMPA1_HUMAN |
| Accession Number | NP_005527 |
| Immunogen | Recombinant human IMPA1 (1-277aa) purified from E. coli |
| Immunogen Region | 1-277aa |
Additional Info
| Function | Phosphatase involved in the dephosphorylation of myo-inositol monophosphates to generate myo-inositol. Is also able to dephosphorylate scyllo-inositol-phosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-1,3-diphosphate and scyllo-inositol-1,4-diphosphate. Also dephosphorylates in vitro other sugar-phosphates including D-galactose-1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate and 2'-AMP. Responsible for the provision of inositol required for synthesis of phosphatidylinositols and polyphosphoinositides, and involved in maintaining normal brain function. Has been implicated as the pharmacological target for lithium (Li(+)) action in brain, which is used to treat bipolar affective disorder. Is equally active with 1D-myo-inositol 1-phosphate, 1D-myo-inositol 3-phosphate and D-galactose 1-phosphate. |
| Protein Name | Inositol Monophosphatase 1Imp 1Impase 1D-Galactose 1-Phosphate PhosphataseInositol-1(Or 4-Monophosphatase 1Lithium-Sensitive Myo-Inositol Monophosphatase A1 |
| Database Links | Reactome: R-HSA-1855183 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Inositol Monophosphatase 1 antibodyAnti-Imp 1 antibodyAnti-Impase 1 antibodyAnti-D-Galactose 1-Phosphate Phosphatase antibodyAnti-Inositol-1(Or 4-Monophosphatase 1 antibodyAnti-Lithium-Sensitive Myo-Inositol Monophosphatase A1 antibodyAnti-IMPA1 antibodyAnti-IMPA antibody |
Information sourced from Uniprot.org