Anti-IMPA1/IMP1 antibody (1-277aa) [AT2G5] (STJA0041776)

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STJA0041776
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Short Description :Mouse monoclonal anti-IMPA1/IMP1 (1-277aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/WB/ICC/IF/FACS
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :AT2G5
Isotype:IgG1k
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:By protein-A affinity chromatography
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:IMPA1
Gene ID:3612
Uniprot ID:IMPA1_HUMAN
Accession Number:NP_005527
Immunogen:Recombinant human IMPA1 (1-277aa) purified from E. coli
Immunogen Region:1-277aa
Function Phosphatase involved in the dephosphorylation of myo-inositol monophosphates to generate myo-inositol. Is also able to dephosphorylate scyllo-inositol-phosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-1,3-diphosphate and scyllo-inositol-1,4-diphosphate. Also dephosphorylates in vitro other sugar-phosphates including D-galactose-1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate and 2'-AMP. Responsible for the provision of inositol required for synthesis of phosphatidylinositols and polyphosphoinositides, and involved in maintaining normal brain function. Has been implicated as the pharmacological target for lithium (Li(+)) action in brain, which is used to treat bipolar affective disorder. Is equally active with 1D-myo-inositol 1-phosphate, 1D-myo-inositol 3-phosphate and D-galactose 1-phosphate.
Protein Name Inositol Monophosphatase 1
Imp 1
Impase 1
D-Galactose 1-Phosphate Phosphatase
Inositol-1(Or 4-Monophosphatase 1
Lithium-Sensitive Myo-Inositol Monophosphatase A1
Database Links Reactome: R-HSA-1855183
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Inositol Monophosphatase 1 antibody
Anti-Imp 1 antibody
Anti-Impase 1 antibody
Anti-D-Galactose 1-Phosphate Phosphatase antibody
Anti-Inositol-1(Or 4-Monophosphatase 1 antibody
Anti-Lithium-Sensitive Myo-Inositol Monophosphatase A1 antibody
Anti-IMPA1 antibody
Anti-IMPA antibody

Information sourced from Uniprot.org

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