| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Interleukin-18 receptor accessory protein (291-340 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200 ELISA 1:10000-20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IL18RAP |
| Gene ID: | 8807 |
| Uniprot ID: | I18RA_HUMAN |
| Immunogen Region: | 291-340 aa |
| Specificity: | The antibody detects endogenous CD218b |
| Immunogen: | Synthetic peptide from the human protein at the amino acid range 291-340 |
| Post Translational Modifications | N-glycosylated. |
| Function | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). |
| Protein Name | Interleukin-18 Receptor Accessory Protein Il-18 Receptor Accessory Protein Il-18racp Accessory Protein-Like Acpl Cd218 Antigen-Like Family Member B Cdw218b Il-1r Accessory Protein-Like Il-1racpl Interleukin-1 Receptor 7 Il-1r-7 Il-1r7 Interleukin-18 Receptor Accessory Protein-Like Interleukin-18 Receptor Beta Il-18r-Beta Il-18rbeta Cd Antigen Cd218b |
| Database Links | Reactome: R-HSA-9012546 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-18 Receptor Accessory Protein antibody Anti-Il-18 Receptor Accessory Protein antibody Anti-Il-18racp antibody Anti-Accessory Protein-Like antibody Anti-Acpl antibody Anti-Cd218 Antigen-Like Family Member B antibody Anti-Cdw218b antibody Anti-Il-1r Accessory Protein-Like antibody Anti-Il-1racpl antibody Anti-Interleukin-1 Receptor 7 antibody Anti-Il-1r-7 antibody Anti-Il-1r7 antibody Anti-Interleukin-18 Receptor Accessory Protein-Like antibody Anti-Interleukin-18 Receptor Beta antibody Anti-Il-18r-Beta antibody Anti-Il-18rbeta antibody Anti-Cd Antigen Cd218b antibody Anti-IL18RAP antibody Anti-IL1R7 antibody |
Information sourced from Uniprot.org