| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Interleukin-18 receptor accessory protein (291-340 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
IL18RAP |
| Gene ID: |
8807 |
| Uniprot ID: |
I18RA_HUMAN |
| Immunogen Region: |
291-340 aa |
| Specificity: |
The antibody detects endogenous CD218b |
| Immunogen: |
Synthetic peptide from the human protein at the amino acid range 291-340 |
| Post Translational Modifications | N-glycosylated. |
| Function | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). |
| Protein Name | Interleukin-18 Receptor Accessory ProteinIl-18 Receptor Accessory ProteinIl-18racpAccessory Protein-LikeAcplCd218 Antigen-Like Family Member BCdw218bIl-1r Accessory Protein-LikeIl-1racplInterleukin-1 Receptor 7Il-1r-7Il-1r7Interleukin-18 Receptor Accessory Protein-LikeInterleukin-18 Receptor BetaIl-18r-BetaIl-18rbetaCd Antigen Cd218b |
| Database Links | Reactome: R-HSA-9012546 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Interleukin-18 Receptor Accessory Protein antibodyAnti-Il-18 Receptor Accessory Protein antibodyAnti-Il-18racp antibodyAnti-Accessory Protein-Like antibodyAnti-Acpl antibodyAnti-Cd218 Antigen-Like Family Member B antibodyAnti-Cdw218b antibodyAnti-Il-1r Accessory Protein-Like antibodyAnti-Il-1racpl antibodyAnti-Interleukin-1 Receptor 7 antibodyAnti-Il-1r-7 antibodyAnti-Il-1r7 antibodyAnti-Interleukin-18 Receptor Accessory Protein-Like antibodyAnti-Interleukin-18 Receptor Beta antibodyAnti-Il-18r-Beta antibodyAnti-Il-18rbeta antibodyAnti-Cd Antigen Cd218b antibodyAnti-IL18RAP antibodyAnti-IL1R7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
