• Western blot analysis of various lysates, using IL12RB1 Rabbit polyclonal antibody (STJ28115) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-IL12RB1 antibody (25-305) (STJ28115)

SKU:
STJ28115

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IL12RB1 (25-305) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL12RB1
Gene ID: 3594
Uniprot ID: I12R1_HUMAN
Immunogen Region: 25-305
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-305 of human IL12RB1 (NP_714912.1).
Immunogen Sequence: RTSECCFQDPPYPDADSGSA SGPRDLRCYRISSDRYECSW QYEGPTAGVSHFLRCCLSSG RCCYFAAGSATRLQFSDQAG VSVLYTVTLWVESWARNQTE KSPEVTLQLYNSVKYEPPLG DIKVSKLAGQLRMEWETPDN QVGAEVQFRHRTPSSPWKLG DCGPQDDDTESCLCPLEMNV AQEFQLRRRQLGSQGSSWSK WSSPVCVPPENPPQPQVRFS VEQLGQDGRRRLTLKEQPT
Function Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Protein Name Interleukin-12 Receptor Subunit Beta-1
Il-12 Receptor Subunit Beta-1
Il-12r Subunit Beta-1
Il-12r-Beta-1
Il-12rb1
Il-12 Receptor Beta Component
Cd Antigen Cd212
Database Links Reactome: R-HSA-9020591
Reactome: R-HSA-9020933
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-12 Receptor Subunit Beta-1 antibody
Anti-Il-12 Receptor Subunit Beta-1 antibody
Anti-Il-12r Subunit Beta-1 antibody
Anti-Il-12r-Beta-1 antibody
Anti-Il-12rb1 antibody
Anti-Il-12 Receptor Beta Component antibody
Anti-Cd Antigen Cd212 antibody
Anti-IL12RB1 antibody
Anti-IL12R antibody
Anti-IL12RB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance