• Western blot analysis of the lysates from 293 cells using RED antibody.
  • Western blot analysis of HELA KB SH-SY5Y 293T 3T3 lysis using IK antibody. Antibody was diluted at 1:2000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).
  • Western blot analysis of lysates from HepG2, MCF-7, COLO, and HeLa cells, using RED Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using IK Polyclonal Antibody diluted at 1：2000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-IK antibody (508-557 aa) (STJ93662)

SKU:
STJ93662

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein Red (508-557 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IK
Gene ID: 3550
Uniprot ID: RED_HUMAN
Immunogen Region: 508-557 aa
Specificity: IK Polyclonal Antibody detects endogenous levels of IK protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RED at the amino acid range 508-557
Function Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species (Probable). Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. (Microbial infection) Required, together with SMU1, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Protein Name Protein Red
Cytokine Ik
Ik Factor
Protein Rer
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytoskeleton
Spindle Pole
Predominantly Present Throughout The Nucleoplasm During Prometaphase
Metaphase And Anaphase
Is Also Detected In Nuclear Foci That Are Not Identical With Cajal Bodies
Starts To Accumulate At Chromosomes During Telophase
And Is Nearly Exclusively Associated With Chromosomes In Newly Divided Cells
Colocalizes With Mad1l1 At Mitotic Spindle Poles During Metaphase And Anaphase
Alternative Antibody Names Anti-Protein Red antibody
Anti-Cytokine Ik antibody
Anti-Ik Factor antibody
Anti-Protein Rer antibody
Anti-IK antibody
Anti-RED antibody
Anti-RER antibody

Information sourced from Uniprot.org

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