| Tissue Specificity | Liver, kidney, lung, and placenta. |
| Post Translational Modifications | Synthesized as a 75-kDa precursor form in the endoplasmic reticulum (ER), and then processed by proteolytic cleavage through various intermediates to yield a 55-kDa mature form, with the release of an 18 kDa polypeptide. The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. |
| Function | Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate. |
| Protein Name | Iduronate 2-SulfataseAlpha-L-Iduronate Sulfate SulfataseIdursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain |
| Database Links | Reactome: R-HSA-2024096Reactome: R-HSA-2024101Reactome: R-HSA-2206296 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Iduronate 2-Sulfatase antibodyAnti-Alpha-L-Iduronate Sulfate Sulfatase antibodyAnti-Idursulfase Cleaved Into - Iduronate 2-Sulfatase 42 Kda Chain - Iduronate 2-Sulfatase 14 Kda Chain antibodyAnti-IDS antibodyAnti-SIDS antibody |
Information sourced from Uniprot.org
