| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hyccin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HYCC1 |
| Gene ID: |
84668 |
| Uniprot ID: |
HYCCI_HUMAN |
| Specificity: |
This antibody detects endogenous levels of FAM126A at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human FAM126A |
| Function | Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. HYCC1 plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P. Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system. May also have a role in the beta-catenin/Lef signaling pathway (Probable). |
| Protein Name | HyccinDown-Regulated By Ctnnb1 Protein A |
| Cellular Localisation | CytoplasmCytosolCell MembraneLocalizes To The Cytosol And Is Recruited To The Plasma Membrane Following Interaction With Other Components Of The Phosphatidylinositol 4-Kinase (Pi4k) Complex |
| Alternative Antibody Names | Anti-Hyccin antibodyAnti-Down-Regulated By Ctnnb1 Protein A antibodyAnti-HYCC1 antibodyAnti-DRCTNNB1A antibodyAnti-FAM126A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
