Anti-HYCC1 antibody (STJA0009327)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FAM126A
General Information
| Short Description | Rabbit polyclonal anti-Hyccin for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HYCC1 |
| Gene ID | 84668 |
| Uniprot ID | HYCCI_HUMAN |
| Immunogen | Synthesized peptide derived from human FAM126A |
| Specificity | This antibody detects endogenous levels of FAM126A at Human, Mouse |
Additional Info
| Function | Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. HYCC1 plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P. Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system. May also have a role in the beta-catenin/Lef signaling pathway (Probable). |
| Protein Name | HyccinDown-Regulated By Ctnnb1 Protein A |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolCell MembraneLocalizes To The Cytosol And Is Recruited To The Plasma Membrane Following Interaction With Other Components Of The Phosphatidylinositol 4-Kinase (Pi4k) Complex |
| Alternative Antibody Names | Anti-Hyccin antibodyAnti-Down-Regulated By Ctnnb1 Protein A antibodyAnti-HYCC1 antibodyAnti-DRCTNNB1A antibodyAnti-FAM126A antibody |
Information sourced from Uniprot.org