Anti-HTR7 antibody [R04-1I4] (STJA0037346)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human 5HT7 Receptor
General Information
| Short Description | Rabbit monoclonal anti-HTR7 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-1I4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HTR7 |
| Gene ID | 3363 |
| Uniprot ID | 5HT7R_HUMAN |
| Immunogen | A synthesized peptide derived from human 5HT7 Receptor |
Additional Info
| Tissue Specificity | Isoform A: Predominant isoform in spleen, caudate and hippocampus. Isoform B: Expressed at lower levels. Isoform D: Minor isoform in terms of expression. |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 75-Ht-75-Ht75-Ht-XSerotonin Receptor 7 |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418555Reactome: R-HSA-9706019 P34969-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 7 antibodyAnti-5-Ht-7 antibodyAnti-5-Ht7 antibodyAnti-5-Ht-X antibodyAnti-Serotonin Receptor 7 antibodyAnti-HTR7 antibody |
Information sourced from Uniprot.org