| Tissue Specificity | Isoform A: Predominant isoform in spleen, caudate and hippocampus. Isoform B: Expressed at lower levels. Isoform D: Minor isoform in terms of expression. |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 75-Ht-75-Ht75-Ht-XSerotonin Receptor 7 |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418555Reactome: R-HSA-9706019 P34969-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 7 antibodyAnti-5-Ht-7 antibodyAnti-5-Ht7 antibodyAnti-5-Ht-X antibodyAnti-Serotonin Receptor 7 antibodyAnti-HTR7 antibody |
Information sourced from Uniprot.org
