Anti-HTR7/5-HT7 antibody (C-Term) (STJ71913)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-HTR7/5-HT7 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 50kDa band observed in lysates of cell line KELLY (calculated MW of 49.5kDa according to NP_000863.1). Recommended concentration: 1-3µg/ml.An additional band of unknown identity |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | HTR7 |
| Gene ID | 3363 |
| Uniprot ID | 5HT7R_HUMAN |
| Accession Number | NP_000863.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | QNADYCRKKGHDS |
| Specificity | This antibody is expected to recognize isoform a (NP_000863.1) only. |
Additional Info
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 75-Ht-75-Ht75-Ht-XSerotonin Receptor 7 |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418555Reactome: R-HSA-9706019 P34969-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 7 antibodyAnti-5-Ht-7 antibodyAnti-5-Ht7 antibodyAnti-5-Ht-X antibodyAnti-Serotonin Receptor 7 antibodyAnti-HTR7 antibody |
Information sourced from Uniprot.org