| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-HTR7/5-HT7 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 50kDa band observed in lysates of cell line KELLY (calculated MW of 49.5kDa according to NP_000863.1). Recommended concentration: 1-3µg/ml.An additional band of unknown identity |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
HTR7 |
| Gene ID: |
3363 |
| Uniprot ID: |
5HT7R_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_000863.1 |
| Specificity: |
This antibody is expected to recognize isoform a (NP_000863.1) only. |
| Immunogen Sequence: |
QNADYCRKKGHDS |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 75-Ht-75-Ht75-Ht-XSerotonin Receptor 7 |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418555Reactome: R-HSA-9706019 P34969-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 7 antibodyAnti-5-Ht-7 antibodyAnti-5-Ht7 antibodyAnti-5-Ht-X antibodyAnti-Serotonin Receptor 7 antibodyAnti-HTR7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
