| Host: | Rabbit |
| Applications: | IF/ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-5-hydroxytryptamine receptor 1E (101-150 aa) is suitable for use in Immunofluorescence, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IF ICC 1:50-300ELISA 1:2000-20000IHC-P 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HTR1E |
| Gene ID: | 3354 |
| Uniprot ID: | 5HT1E_HUMAN |
| Immunogen Region: | 101-150 aa |
| Specificity: | SR-1E Polyclonal Antibody detects endogenous levels of SR-1E protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human 5-HT-1E at the amino acid range 101-150 |
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1E is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 1e5-Ht-1e5-Ht1eS31Serotonin Receptor 1e |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 1e antibodyAnti-5-Ht-1e antibodyAnti-5-Ht1e antibodyAnti-S31 antibodyAnti-Serotonin Receptor 1e antibodyAnti-HTR1E antibody |
Information sourced from Uniprot.org