Anti-HTR1E antibody (101-150 aa) (STJ95759)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human 5-HT-1E at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-5-hydroxytryptamine receptor 1E (101-150 aa) for use in IF, ELISA and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IF ICC 1:50-300ELISA 1:2000-20000IHC-P 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HTR1E |
| Gene ID | 3354 |
| Uniprot ID | 5HT1E_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human 5-HT-1E at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | SR-1E Polyclonal Antibody detects endogenous levels of SR-1E protein. |
Additional Info
| Function | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1E is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. |
| Protein Name | 5-Hydroxytryptamine Receptor 1e5-Ht-1e5-Ht1eS31Serotonin Receptor 1e |
| Database Links | Reactome: R-HSA-390666Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 1e antibodyAnti-5-Ht-1e antibodyAnti-5-Ht1e antibodyAnti-S31 antibodyAnti-Serotonin Receptor 1e antibodyAnti-HTR1E antibody |
Information sourced from Uniprot.org