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Anti-HSD3B2 antibody (1-287) (STJ26181)

Immunofluorescence analysis of A-549 cells using HSD3B2 Rabbit polyclonal antibody (STJ26181). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with HSD3B2, using HSD3B2 Rabbit polyclonal antibody (STJ26181) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 0. 5s.

Anti-HSD3B2 antibody (1-287) (STJ26181)

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STJ26181

£169.50 - £449.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-HSD3B2 (1-287) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:100-1:500 IF/ICC 1:10-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	HSD3B2
Gene ID:	3284
Uniprot ID:	3BHS2_HUMAN
Immunogen Region:	1-287
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1).
Immunogen Sequence:	MGWSCLVTGAGGLLGQRIVR LLVEEKELKEIRALDKAFRP ELREEFSKLQNRTKLTVLEG DILDEPFLKRACQDVSVVIH TACIIDVFGVTHRESIMNVN VKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNG HEEEPLENTWPTPYPYSKKL AEKAVLAANGWNLKNGDTLY TCALRPTYIYGEGGPFLSAS INEALNNNGILSSVGKFSTV NPVYVGNVAWAHILALRAL

Tissue Specificity	Expressed in adrenal gland, testis and ovary.
Function	3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Protein Name	3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii 3-Beta-Hsd Ii 3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase 3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase Progesterone Reductase - Steroid Delta-Isomerase Delta-5-3-Ketosteroid Isomerase
Database Links	Reactome: R-HSA-193048 Reactome: R-HSA-193993 Reactome: R-HSA-194002
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Membrane Protein Mitochondrion Membrane
Alternative Antibody Names	Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2 antibody Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii antibody Anti-3-Beta-Hsd Ii antibody Anti-3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase antibody Anti-3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase antibody Anti-Progesterone Reductase - Steroid Delta-Isomerase antibody Anti-Delta-5-3-Ketosteroid Isomerase antibody Anti-HSD3B2 antibody Anti-HSDB3B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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