Anti-HSD3B2 antibody (1-287) (STJ26181)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HSD3B2 (1-287) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSD3B2 |
| Gene ID | 3284 |
| Uniprot ID | 3BHS2_HUMAN |
| Immunogen Region | 1-287 |
| Immunogen Sequence | MGWSCLVTGAGGLLGQRIVR LLVEEKELKEIRALDKAFRP ELREEFSKLQNRTKLTVLEG DILDEPFLKRACQDVSVVIH TACIIDVFGVTHRESIMNVN VKGTQLLLEACVQASVPVFI YTSSIEVAGPNSYKEIIQNG HEEEPLENTWPTPYPYSKKL AEKAVLAANGWNLKNGDTLY TCALRPTYIYGEGGPFLSAS INEALNNNGILSSVGKFSTV NPVYVGNVAWAHILALRAL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1). |
Additional Info
| Tissue Specificity | Expressed in adrenal gland, testis and ovary. |
| Function | 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. |
| Protein Name | 3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 23 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii3-Beta-Hsd Ii3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase3-Beta-Hydroxy-5-Ene Steroid DehydrogenaseProgesterone Reductase - Steroid Delta-IsomeraseDelta-5-3-Ketosteroid Isomerase |
| Database Links | Reactome: R-HSA-193048Reactome: R-HSA-193993Reactome: R-HSA-194002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinMitochondrion Membrane |
| Alternative Antibody Names | Anti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2 antibodyAnti-3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type Ii antibodyAnti-3-Beta-Hsd Ii antibodyAnti-3-Beta-Hsd Adrenal And Gonadal Type Includes - 3-Beta-Hydroxy-Delta(5-Steroid Dehydrogenase antibodyAnti-3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase antibodyAnti-Progesterone Reductase - Steroid Delta-Isomerase antibodyAnti-Delta-5-3-Ketosteroid Isomerase antibodyAnti-HSD3B2 antibodyAnti-HSDB3B antibody |
Information sourced from Uniprot.org