| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HPX (24-245) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HPX |
| Gene ID: |
3263 |
| Uniprot ID: |
HEMO_HUMAN |
| Immunogen Region: |
24-245 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-245 of human Hemopexin (Hemopexin (HPX) ) (NP_000604.1). |
| Immunogen Sequence: |
TPLPPTSAHGNVAEGETKPD PDVTERCSDGWSFDATTLDD NGTMLFFKGEFVWKSHKWDR ELISERWKNFPSPVDAAFRQ GHNSVFLIKGDKVWVYPPEK KEKGYPKLLQDEFPGIPSPL DAAVECHRGECQAEGVLFFQ GDREWFWDLATGTMKERSWP AVGNCSSALRWLGRYYCFQG NQFLRFDPVRGEVPPRYPRD VRDYFMPCPGRGHGHRNGTG HG |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
| Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
| Protein Name | HemopexinBeta-1b-Glycoprotein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Hemopexin antibodyAnti-Beta-1b-Glycoprotein antibodyAnti-HPX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
