Anti-HPX antibody (24-245) (STJ27570)

Name: Anti-HPX antibody (24-245) (STJ27570)
SKU: STJ27570
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ27570

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Short Description	Rabbit polyclonal HPX (24-245) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	HPX
Gene ID	3263
Uniprot ID	HEMO_HUMAN
Immunogen Region	24-245
Immunogen Sequence	TPLPPTSAHGNVAEGETKPD PDVTERCSDGWSFDATTLDD NGTMLFFKGEFVWKSHKWDR ELISERWKNFPSPVDAAFRQ GHNSVFLIKGDKVWVYPPEK KEKGYPKLLQDEFPGIPSPL DAAVECHRGECQAEGVLFFQ GDREWFWDLATGTMKERSWP AVGNCSSALRWLGRYYCFQG NQFLRFDPVRGEVPPRYPRD VRDYFMPCPGRGHGHRNGTG HG
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 24-245 of human Hemopexin (Hemopexin (HPX) ) (NP_000604.1).

Tissue Specificity	Expressed by the liver and secreted in plasma.
Post Translational Modifications	N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29.
Function	Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Protein Name	Hemopexin Beta-1b-Glycoprotein
Database Links	Reactome: R-HSA-2168880
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Hemopexin antibody Anti-Beta-1b-Glycoprotein antibody Anti-HPX antibody

Information sourced from Uniprot.org