Anti-CLTA antibody (1-218) (STJ23172)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CLTA (1-218) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLTA |
| Gene ID | 1211 |
| Uniprot ID | CLCA_HUMAN |
| Immunogen Region | 1-218 |
| Immunogen Sequence | MAELDPFGAPAGAPGGPALG NGVAGAGEEDPAAAFLAQQE SEIAGIENDEAFAILDGGAP GPQPHGEPPGGPDAVDGVMN GEYYQESNGPTDSYAAISQV DRLQSEPESIRKWREEQMER LEALDANSRKQEAEWKEKAI KELEEWYARQDEQLQKTKAN NRAAEEAFVNDIDESSPGTE WERVARLCDFNPKSSKQAKD VSRMRSVLISLKQAPLVH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human CLTA (NP_001824.1). |
Additional Info
| Function | Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. |
| Protein Name | Clathrin Light Chain ALca |
| Database Links | Reactome: R-HSA-168275Reactome: R-HSA-177504Reactome: R-HSA-190873Reactome: R-HSA-196025Reactome: R-HSA-2132295Reactome: R-HSA-3928665Reactome: R-HSA-432720Reactome: R-HSA-432722 P09496-1Reactome: R-HSA-437239Reactome: R-HSA-5099900Reactome: R-HSA-5140745Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8866427Reactome: R-HSA-8964038 |
| Cellular Localisation | Cytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideMembraneCoated PitCytoplasmCytoskeletonSpindleCytoplasmic Face Of Coated Pits And VesiclesIn Complex With Tacc3 And Ckap5 (Forming The Tacc3/Ch-Tog/Clathrin Complex) Localized To Inter-Microtubule Bridges In Mitotic Spindles |
| Alternative Antibody Names | Anti-Clathrin Light Chain A antibodyAnti-Lca antibodyAnti-CLTA antibody |
Information sourced from Uniprot.org