Anti-HPN/Hepsin antibody [SAA1938] (STJA0020366)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Serine Protease Hepsin antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1938 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | HPN |
| Gene ID | 3249 |
| Uniprot ID | HEPS_HUMAN |
Additional Info
| Function | Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization. |
| Protein Name | Serine Protease HepsinTransmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Serine Protease Hepsin antibodyAnti-Transmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain antibodyAnti-HPN antibodyAnti-TMPRSS1 antibody |
Information sourced from Uniprot.org