Anti-HPN/Hepsin antibody [SAA1938] (STJA0020366)

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STJA0020366
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal anti-Serine Protease Hepsin for use in ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : SAA1938
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: HPN
Gene ID: 3249
Uniprot ID: HEPS_HUMAN
Function Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.
Protein Name Serine Protease Hepsin
Transmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain
Database Links Reactome: R-HSA-6806942
Reactome: R-HSA-8852405
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Apical Cell Membrane
Alternative Antibody Names Anti-Serine Protease Hepsin antibody
Anti-Transmembrane Protease Serine 1 Cleaved Into - Serine Protease Hepsin Non-Catalytic Chain - Serine Protease Hepsin Catalytic Chain antibody
Anti-HPN antibody
Anti-TMPRSS1 antibody

Information sourced from Uniprot.org