| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-HPCA (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | HPCA |
| Gene ID: | 3208 |
| Uniprot ID: | HPCA_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for hippocalcin. |
| Immunogen: | A synthetic peptide from the c-terminal region of human Hippocalcin (HPCA) conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | Myristoylation facilitates association with membranes. |
| Function | Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases. |
| Protein Name | Neuron-Specific Calcium-Binding Protein HippocalcinCalcium-Binding Protein Bdr-2 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinAssociation With Membranes Is Calcium-DependentEnriched In The Perinuclear RegionProbably At The Trans Golgi Network In Response To Calcium |
| Alternative Antibody Names | Anti-Neuron-Specific Calcium-Binding Protein Hippocalcin antibodyAnti-Calcium-Binding Protein Bdr-2 antibodyAnti-HPCA antibodyAnti-BDR2 antibody |
Information sourced from Uniprot.org
