Anti-HPCA antibody (C-Term) (STJ13101224)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the c-terminal region of human Hippocalcin (HPCA) conjugated to blue carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-HPCA (C-Term) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | HPCA |
| Gene ID | 3208 |
| Uniprot ID | HPCA_HUMAN |
| Immunogen | A synthetic peptide from the c-terminal region of human Hippocalcin (HPCA) conjugated to blue carrier protein was used as the antigen. |
| Immunogen Region | C-Term |
| Specificity | Specific for hippocalcin. |
Additional Info
| Post Translational Modifications | Myristoylation facilitates association with membranes. |
| Function | Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels. May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases. |
| Protein Name | Neuron-Specific Calcium-Binding Protein HippocalcinCalcium-Binding Protein Bdr-2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinAssociation With Membranes Is Calcium-DependentEnriched In The Perinuclear RegionProbably At The Trans Golgi Network In Response To Calcium |
| Alternative Antibody Names | Anti-Neuron-Specific Calcium-Binding Protein Hippocalcin antibodyAnti-Calcium-Binding Protein Bdr-2 antibodyAnti-HPCA antibodyAnti-BDR2 antibody |
Information sourced from Uniprot.org