Anti-HOOK1 antibody (201-251) (STJA0006430)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human HOOK1 AA range: 201-251
STJA0006430
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General Information

Short DescriptionRabbit polyclonal anti-Protein Hook homolog 1 (201-251) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:1000-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHOOK1
Gene ID51361
Uniprot IDHOOK1_HUMAN
ImmunogenSynthesized peptide derived from human HOOK1 AA range: 201-251
Immunogen Region201-251
SpecificityThis antibody detects endogenous levels of human HOOK1

Additional Info

Protein Name Protein Hook Homolog 1
H-Hook1
Hhk1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Localizes To Punctate Cytoplasmic Foci Which Do Not Appear To Overlap With Early Or Late Endosomes
The Endoplasmic Reticulum
Multivesicular Bodies (Mvbs)
Lysosomes
Or Mitochondria
Often Found In Close Association With Microtubules
Does Not Associate With The Golgi Complex
During Spermiogenesis
It Localizes To The Manchette In Spermatids From Steps 8-10
It Is Also Present Between The Microtubule Manchette And The Nucleus
During Manchette Elongation
It Is Preferentially Localized To The Nuclear Ring Of The Manchette
Whereas The Strong Localization To The Manchette Decreases
In More Mature Spermatids
While The Manchette Migrates Posteriorly
It Localizes To Punctuates Spots
At Later Stages Of Spermatid Differentiation
The Punctuate Expression Pattern Is Found At Both The Attachment Site And The Proximal End Of The Elongated Manchette
In Contrast
It Is Not Present In Mature Spermatozoa
Alternative Antibody Names Anti-Protein Hook Homolog 1 antibody
Anti-H-Hook1 antibody
Anti-Hhk1 antibody
Anti-HOOK1 antibody

Information sourced from Uniprot.org

Citations

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