| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Protein Hook homolog 1 (201-251) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HOOK1 |
| Gene ID: |
51361 |
| Uniprot ID: |
HOOK1_HUMAN |
| Immunogen Region: |
201-251 |
| Specificity: |
This antibody detects endogenous levels of human HOOK1 |
| Immunogen: |
Synthesized peptide derived from human HOOK1 AA range: 201-251 |
| Protein Name | Protein Hook Homolog 1H-Hook1Hhk1 |
| Cellular Localisation | CytoplasmCytoskeletonLocalizes To Punctate Cytoplasmic Foci Which Do Not Appear To Overlap With Early Or Late EndosomesThe Endoplasmic ReticulumMultivesicular Bodies (Mvbs)LysosomesOr MitochondriaOften Found In Close Association With MicrotubulesDoes Not Associate With The Golgi ComplexDuring SpermiogenesisIt Localizes To The Manchette In Spermatids From Steps 8-10It Is Also Present Between The Microtubule Manchette And The NucleusDuring Manchette ElongationIt Is Preferentially Localized To The Nuclear Ring Of The ManchetteWhereas The Strong Localization To The Manchette DecreasesIn More Mature SpermatidsWhile The Manchette Migrates PosteriorlyIt Localizes To Punctuates SpotsAt Later Stages Of Spermatid DifferentiationThe Punctuate Expression Pattern Is Found At Both The Attachment Site And The Proximal End Of The Elongated ManchetteIn ContrastIt Is Not Present In Mature Spermatozoa |
| Alternative Antibody Names | Anti-Protein Hook Homolog 1 antibodyAnti-H-Hook1 antibodyAnti-Hhk1 antibodyAnti-HOOK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
