Anti-HNRNPF antibody (315-415 aa) (STJ11104962)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11104962
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General Information

Short DescriptionRabbit polyclonal Heterogeneous Nuclear Ribonucleoprotein F (315-415 aa) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHNRNPF
Gene ID3185
Uniprot IDHNRPF_HUMAN
Immunogen Region315-415 aa
Immunogen SequenceVRVHIEIGPDGRVTGEADVE FATHEEAVAAMSKDRANMQH RYIELFLNSTTGASNGAYSS QVMQGMGVSAAQATYSGLES QSVSGCYGAGYSGQNSMGGY D
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 315-415 of human HNRNPF. (NP_004957.1).

Additional Info

Tissue Specificity Expressed ubiquitously.
Post Translational Modifications Sumoylated.
Function Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Protein Name Heterogeneous Nuclear Ribonucleoprotein F
Hnrnp F
Nucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed
Database Links Reactome: R-HSA-6803529
Reactome: R-HSA-72163
Reactome: R-HSA-72203
Reactome: R-HSA-8950505
Cellular Localisation Nucleus
Nucleoplasm
Alternative Antibody Names Anti-Heterogeneous Nuclear Ribonucleoprotein F antibody
Anti-Hnrnp F antibody
Anti-Nucleolin-Like Protein Mcs94-1 Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein F - N-Terminally Processed antibody
Anti-HNRNPF antibody
Anti-HNRPF antibody

Information sourced from Uniprot.org

Citations

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