| Short Description : | Rabbit polyclonal HGFAC (408-655) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HGFAC |
| Gene ID: | 3083 |
| Uniprot ID: | HGFA_HUMAN |
| Immunogen Region: | 408-655 |
| Immunogen Sequence: | IIGGSSSLPGSHPWLAAIYI GDSFCAGSLVHTCWVVSAAH CFSHSPPRDSVSVVLGQHFF NRTTDVTQTFGIEKYIPYTL YSVFNPSDHDLVLIRLKKKG DRCATRSQFVQPICLPEPGS TFPAGHKCQIAGWGHLDENV SGYSSSLREALVPLVADHKC SSPEVYGADISPNMLCAGYF DCKSDACQGDSGGPLACEKN GVAYLYGIISWGDGCGRLHK PGVYTRVANYVDWINDRIR |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 408-655 of human HGFAC (NP_001519.1). |
| Tissue Specificity | Liver. |
| Post Translational Modifications | The active form of HGFAC presents in the serum is derived from the COOH-terminal region of the precursor by the cleavage of bonds between Arg-372 and Val-373 and Arg-407 and Ile-408. |
| Function | Serine protease that hydrolyzes the inactive zymogen hepatocyte growth factor (HGFsc) to an activated disulfide-linked heterodimer, then initiating hepatocyte growth factor receptor signaling pathway. |
| Protein Name | Hepatocyte Growth Factor Activator Serine ProteaseHgf ActivatorHgfaHgfa Serine ProteaseSerine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain |
| Database Links | Reactome: R-HSA-6806942 |
| Cellular Localisation | SecretedExists As An Inactive Zymogen In PlasmaExists As An Active Heterodimeric Form In Serum |
| Alternative Antibody Names | Anti-Hepatocyte Growth Factor Activator Serine Protease antibodyAnti-Hgf Activator antibodyAnti-Hgfa antibodyAnti-Hgfa Serine Protease antibodyAnti-Serine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain antibodyAnti-HGFAC antibody |
Information sourced from Uniprot.org
