Anti-HGFAC antibody (408-655) (STJ112153)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HGFAC (408-655) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HGFAC |
| Gene ID | 3083 |
| Uniprot ID | HGFA_HUMAN |
| Immunogen Region | 408-655 |
| Immunogen Sequence | IIGGSSSLPGSHPWLAAIYI GDSFCAGSLVHTCWVVSAAH CFSHSPPRDSVSVVLGQHFF NRTTDVTQTFGIEKYIPYTL YSVFNPSDHDLVLIRLKKKG DRCATRSQFVQPICLPEPGS TFPAGHKCQIAGWGHLDENV SGYSSSLREALVPLVADHKC SSPEVYGADISPNMLCAGYF DCKSDACQGDSGGPLACEKN GVAYLYGIISWGDGCGRLHK PGVYTRVANYVDWINDRIR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 408-655 of human HGFAC (NP_001519.1). |
Additional Info
| Tissue Specificity | Liver. |
| Post Translational Modifications | The active form of HGFAC presents in the serum is derived from the COOH-terminal region of the precursor by the cleavage of bonds between Arg-372 and Val-373 and Arg-407 and Ile-408. |
| Function | Serine protease that hydrolyzes the inactive zymogen hepatocyte growth factor (HGFsc) to an activated disulfide-linked heterodimer, then initiating hepatocyte growth factor receptor signaling pathway. |
| Protein Name | Hepatocyte Growth Factor Activator Serine ProteaseHgf ActivatorHgfaHgfa Serine ProteaseSerine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain |
| Database Links | Reactome: R-HSA-6806942 |
| Cellular Localisation | SecretedExists As An Inactive Zymogen In PlasmaExists As An Active Heterodimeric Form In Serum |
| Alternative Antibody Names | Anti-Hepatocyte Growth Factor Activator Serine Protease antibodyAnti-Hgf Activator antibodyAnti-Hgfa antibodyAnti-Hgfa Serine Protease antibodyAnti-Serine Protease Hgfac Cleaved Into - Hepatocyte Growth Factor Activator Short Chain - Hepatocyte Growth Factor Activator Long Chain antibodyAnti-HGFAC antibody |
Information sourced from Uniprot.org