Anti-Hemoglobin Subunit alpha antibody [R06-5F7] (STJA0035990)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Hemoglobin subunit alpha
General Information
| Short Description | Rabbit monoclonal anti-Hemoglobin Subunit alpha for use in WB, IHC-P, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5F7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | HBA1.HBA2 |
| Gene ID | 3039/3040 |
| Uniprot ID | HBA_HUMAN |
| Immunogen | A synthesized peptide derived from human Hemoglobin subunit alpha |
Additional Info
| Tissue Specificity | Red blood cells. |
| Post Translational Modifications | The initiator Met is not cleaved in variant Thionville and is acetylated. |
| Function | Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin: Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling. |
| Protein Name | Hemoglobin Subunit AlphaAlpha-GlobinHemoglobin Alpha Chain Cleaved Into - Hemopressin |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-2168880Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Hemoglobin Subunit Alpha antibodyAnti-Alpha-Globin antibodyAnti-Hemoglobin Alpha Chain Cleaved Into - Hemopressin antibodyAnti-HBA1.HBA2 antibody |
Information sourced from Uniprot.org