Anti-HDAC10 antibody (STJA0005751)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
Immunogenrecombinant human HDAC 10 protein
General Information
| Short Description | Rabbit polyclonal anti-HDAC10 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Antigen Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | PBS + 0.02% NaN3 |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HDAC10 |
| Gene ID | 83933 |
| Uniprot ID | HDA10_HUMAN |
| Immunogen | recombinant human HDAC 10 protein |
| Specificity | Reacts with human HDAC10 protein. |
Additional Info
| Function | Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair. |
| Protein Name | Polyamine Deacetylase Hdac10Histone Deacetylase 10Hd10 |
| Database Links | Reactome: R-HSA-2122947Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-3214815Reactome: R-HSA-350054 |
| Cellular Localisation | CytoplasmNucleusExcluded From Nucleoli |
| Alternative Antibody Names | Anti-Polyamine Deacetylase Hdac10 antibodyAnti-Histone Deacetylase 10 antibodyAnti-Hd10 antibodyAnti-HDAC10 antibody |
Information sourced from Uniprot.org