Anti-HDAC10 antibody (STJA0005751)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
Immunogenrecombinant human HDAC 10 protein
STJA0005751-100
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General Information

Short DescriptionRabbit polyclonal anti-HDAC10 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
PurificationAntigen Affinity Purified
Dilution RangeWB 1:500-1:1000
FormulationPBS + 0.02% NaN3
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHDAC10
Gene ID83933
Uniprot IDHDA10_HUMAN
Immunogenrecombinant human HDAC 10 protein
SpecificityReacts with human HDAC10 protein.

Additional Info

Function Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Histone deacetylase activity has been observed in vitro. Has also been shown to be involved in MSH2 deacetylation. The physiological relevance of protein/histone deacetylase activity is unclear and could be very weak. May play a role in the promotion of late stages of autophagy, possibly autophagosome-lysosome fusion and/or lysosomal exocytosis in neuroblastoma cells. May play a role in homologous recombination. May promote DNA mismatch repair.
Protein Name Polyamine Deacetylase Hdac10
Histone Deacetylase 10
Hd10
Database Links Reactome: R-HSA-2122947
Reactome: R-HSA-2644606
Reactome: R-HSA-2894862
Reactome: R-HSA-3214815
Reactome: R-HSA-350054
Cellular Localisation Cytoplasm
Nucleus
Excluded From Nucleoli
Alternative Antibody Names Anti-Polyamine Deacetylase Hdac10 antibody
Anti-Histone Deacetylase 10 antibody
Anti-Hd10 antibody
Anti-HDAC10 antibody

Information sourced from Uniprot.org

Citations

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