Anti-HBA2 antibody (1-142) (STJ110725)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HBA2 (1-142) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HBA1.HBA2 |
| Gene ID | 3039/3040 |
| Uniprot ID | HBA_HUMAN |
| Immunogen Region | 1-142 |
| Immunogen Sequence | MVLSPADKTNVKAAWGKVGA HAGEYGAEALERMFLSFPTT KTYFPHFDLSHGSAQVKGHG KKVADALTNAVAHVDDMPNA LSALSDLHAHKLRVDPVNFK LLSHCLLVTLAAHLPAEFTP AVHASLDKFLASVSTVLTSK YR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human HBA2 (NP_000508.1). |
Additional Info
| Tissue Specificity | Red blood cells. |
| Post Translational Modifications | The initiator Met is not cleaved in variant Thionville and is acetylated. |
| Function | Involved in oxygen transport from the lung to the various peripheral tissues. Hemopressin: Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling. |
| Protein Name | Hemoglobin Subunit AlphaAlpha-GlobinHemoglobin Alpha Chain Cleaved Into - Hemopressin |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-2168880Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Hemoglobin Subunit Alpha antibodyAnti-Alpha-Globin antibodyAnti-Hemoglobin Alpha Chain Cleaved Into - Hemopressin antibodyAnti-HBA1.HBA2 antibody |
Information sourced from Uniprot.org