Anti-HAUS6 antibody (676-955) (STJ23620)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HAUS6 (676-955) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HAUS6 |
| Gene ID | 54801 |
| Uniprot ID | HAUS6_HUMAN |
| Immunogen Region | 676-955 |
| Immunogen Sequence | DEPPTQNQSDLLNKKVICKQ DLECLAFTKLSETSRMETFS PAVGNRIDVMGGSEEEFMKI LDHLEVSCNKPSTNKTMLWN SFQISSGISSKSFKDNDFGI LHETLPEEVGHLSFNSSSSS EANFKLEPNSPMHGGTLLED VVGGRQTTPESDFNLQALRS RYEALKKSLSKKREESYLSN SQTPERHKPELSPTPQNVQT DDTLNFLDTCDLHTEHIKPS LRTSIGERKRSLSPLIKFS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 676-955 of human HAUS6 (NP_060115.3). |
Additional Info
| Post Translational Modifications | Phosphorylated during mitosis. |
| Function | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. |
| Protein Name | Haus Augmin-Like Complex Subunit 6 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMicrotubule Organizing CenterCentrosomeLocalizes To Interphase Centrosomes And To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Haus Augmin-Like Complex Subunit 6 antibodyAnti-HAUS6 antibodyAnti-DGT6 antibodyAnti-FAM29A antibodyAnti-KIAA1574 antibody |
Information sourced from Uniprot.org