| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HAUS6 |
| Gene ID: | 54801 |
| Uniprot ID: | HAUS6_HUMAN |
| Immunogen Region: | 676-955 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 676-955 of human HAUS6 (NP_060115.3). |
| Immunogen Sequence: | DEPPTQNQSDLLNKKVICKQ DLECLAFTKLSETSRMETFS PAVGNRIDVMGGSEEEFMKI LDHLEVSCNKPSTNKTMLWN SFQISSGISSKSFKDNDFGI LHETLPEEVGHLSFNSSSSS EANFKLEPNSPMHGGTLLED VVGGRQTTPESDFNLQALRS RYEALKKSLSKKREESYLSN SQTPERHKPELSPTPQNVQT DDTLNFLDTCDLHTEHIKPS LRTSIGERKRSLSPLIKFS |
| Post Translational Modifications | Phosphorylated during mitosis. |
| Function | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. |
| Protein Name | Haus Augmin-Like Complex Subunit 6 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMicrotubule Organizing CenterCentrosomeLocalizes To Interphase Centrosomes And To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Haus Augmin-Like Complex Subunit 6 antibodyAnti-HAUS6 antibodyAnti-DGT6 antibodyAnti-FAM29A antibodyAnti-KIAA1574 antibody |
Information sourced from Uniprot.org
