• Western blot analysis of various lysates using Guanylyl Cyclase beta 1 (GUCY1B3) Rabbit polyclonal antibody (STJ117471) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30S.

Anti-GUCY1B3 antibody (1-250) (STJ117471)

SKU:
STJ117471

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GUCY1B3 (1-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GUCY1B1
Gene ID: 2983
Uniprot ID: GCYB1_HUMAN
Immunogen Region: 1-250
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Guanylyl Cyclase beta 1 (Guanylyl Cyclase beta 1 (GUCY1B3) ) (NP_000848.1).
Immunogen Sequence: MYGFVNHALELLVIRNYGPE VWEDIKKEAQLDEEGQFLVR IIYDDSKTYDLVAAASKVLN LNAGEILQMFGKMFFVFCQE SGYDTILRVLGSNVREFLQN LDALHDHLATIYPGMRAPSF RCTDAEKGKGLILHYYSERE GLQDIVIGIIKTVAQQIHGT EIDMKVIQQRNEECDHTQFL IEEKESKEEDFYEDLDRFEE NGTQESRISPYTFCKAFPFH IIFDRDLVVTQCGNAIYRV
Tissue Specificity Detected in brain cortex and cerebellum (at protein level).
Function Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Protein Name Guanylate Cyclase Soluble Subunit Beta-1
Gcs-Beta-1
Guanylate Cyclase Soluble Subunit Beta-3
Gcs-Beta-3
Soluble Guanylate Cyclase Small Subunit
Database Links Reactome: R-HSA-392154
Reactome: R-HSA-445355
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Guanylate Cyclase Soluble Subunit Beta-1 antibody
Anti-Gcs-Beta-1 antibody
Anti-Guanylate Cyclase Soluble Subunit Beta-3 antibody
Anti-Gcs-Beta-3 antibody
Anti-Soluble Guanylate Cyclase Small Subunit antibody
Anti-GUCY1B1 antibody
Anti-GUC1B3 antibody
Anti-GUCSB3 antibody
Anti-GUCY1B3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance