| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GUCY1B1 |
| Gene ID: | 2983 |
| Uniprot ID: | GCYB1_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Guanylyl Cyclase beta 1 (Guanylyl Cyclase beta 1 (GUCY1B3) ) (NP_000848.1). |
| Immunogen Sequence: | MYGFVNHALELLVIRNYGPE VWEDIKKEAQLDEEGQFLVR IIYDDSKTYDLVAAASKVLN LNAGEILQMFGKMFFVFCQE SGYDTILRVLGSNVREFLQN LDALHDHLATIYPGMRAPSF RCTDAEKGKGLILHYYSERE GLQDIVIGIIKTVAQQIHGT EIDMKVIQQRNEECDHTQFL IEEKESKEEDFYEDLDRFEE NGTQESRISPYTFCKAFPFH IIFDRDLVVTQCGNAIYRV |
| Tissue Specificity | Detected in brain cortex and cerebellum (at protein level). |
| Function | Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP. |
| Protein Name | Guanylate Cyclase Soluble Subunit Beta-1Gcs-Beta-1Guanylate Cyclase Soluble Subunit Beta-3Gcs-Beta-3Soluble Guanylate Cyclase Small Subunit |
| Database Links | Reactome: R-HSA-392154Reactome: R-HSA-445355 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Guanylate Cyclase Soluble Subunit Beta-1 antibodyAnti-Gcs-Beta-1 antibodyAnti-Guanylate Cyclase Soluble Subunit Beta-3 antibodyAnti-Gcs-Beta-3 antibodyAnti-Soluble Guanylate Cyclase Small Subunit antibodyAnti-GUCY1B1 antibodyAnti-GUC1B3 antibodyAnti-GUCSB3 antibodyAnti-GUCY1B3 antibody |
Information sourced from Uniprot.org
