Anti-GUCA2B antibody (1-100) (STJ110688)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GUCA2B (1-100) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GUCA2B |
| Gene ID | 2981 |
| Uniprot ID | GUC2B_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MGCRAASGLLPGVAVVLLLL LQSTQSVYIQYQGFRVQLES MKKLSDLEAQWAPSPRLQAQ SLLPAVCHHPALPQDLQPVC ASQEASSIFKTLRTIANDDC |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GUCA2B (NP_009033.1). |
Additional Info
| Tissue Specificity | Stomach and intestine. |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. |
| Protein Name | Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2Guanylate Cyclase C-Activating Peptide IiGcap-Ii - UroguanylinUgn |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2 antibodyAnti-Guanylate Cyclase C-Activating Peptide Ii antibodyAnti-Gcap-Ii - Uroguanylin antibodyAnti-Ugn antibodyAnti-GUCA2B antibody |
Information sourced from Uniprot.org