| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GUCA2B |
| Gene ID: | 2981 |
| Uniprot ID: | GUC2B_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GUCA2B (NP_009033.1). |
| Immunogen Sequence: | MGCRAASGLLPGVAVVLLLL LQSTQSVYIQYQGFRVQLES MKKLSDLEAQWAPSPRLQAQ SLLPAVCHHPALPQDLQPVC ASQEASSIFKTLRTIANDDC |
| Tissue Specificity | Stomach and intestine. |
| Function | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport. |
| Protein Name | Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2Guanylate Cyclase C-Activating Peptide IiGcap-Ii - UroguanylinUgn |
| Database Links | Reactome: R-HSA-8935690 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2 antibodyAnti-Guanylate Cyclase C-Activating Peptide Ii antibodyAnti-Gcap-Ii - Uroguanylin antibodyAnti-Ugn antibodyAnti-GUCA2B antibody |
Information sourced from Uniprot.org