Anti-GTDC1 antibody (273-323 aa) (STJ195917)

SKU:
STJ195917
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Glycosyltransferase-like domain-containing protein 1 (273-323 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:GTDC1
Gene ID:79712
Uniprot ID:QTMAN_HUMAN
Immunogen:Synthesized peptide derived from the human GTDC1 at the amino acid range 273-323
Immunogen Region:273-323 aa
Specificity:This antibody detects endogenous levels of GTDC1 at Human/Mouse/Rat
Function Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.
Protein Name Trna-Queuosine Alpha-Mannosyltransferase
Qtman
Glycosyltransferase-Like Domain-Containing Protein 1
Mannosyltransferase-Like Protein Xa
Mat-Xa
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Trna-Queuosine Alpha-Mannosyltransferase antibody
Anti-Qtman antibody
Anti-Glycosyltransferase-Like Domain-Containing Protein 1 antibody
Anti-Mannosyltransferase-Like Protein Xa antibody
Anti-Mat-Xa antibody
Anti-GTDC1 antibody
Anti-QTMAN antibody

Information sourced from Uniprot.org