Anti-GTDC1 antibody (273-323 aa) (STJ195917)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human GTDC1 at the amino acid range 273-323
STJ195917
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General Information

Short DescriptionRabbit polyclonal anti-Glycosyltransferase-like domain-containing protein 1 (273-323 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGTDC1
Gene ID79712
Uniprot IDQTMAN_HUMAN
ImmunogenSynthesized peptide derived from the human GTDC1 at the amino acid range 273-323
Immunogen Region273-323 aa
SpecificityThis antibody detects endogenous levels of GTDC1 at Human/Mouse/Rat

Additional Info

Function Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34). Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation.
Protein Name Trna-Queuosine Alpha-Mannosyltransferase
Qtman
Glycosyltransferase-Like Domain-Containing Protein 1
Mannosyltransferase-Like Protein Xa
Mat-Xa
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Trna-Queuosine Alpha-Mannosyltransferase antibody
Anti-Qtman antibody
Anti-Glycosyltransferase-Like Domain-Containing Protein 1 antibody
Anti-Mannosyltransferase-Like Protein Xa antibody
Anti-Mat-Xa antibody
Anti-GTDC1 antibody
Anti-QTMAN antibody

Information sourced from Uniprot.org

Citations

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