Anti-GRPEL2 antibody (33-225) (STJ110637)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GRPEL2 (33-225) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GRPEL2 |
| Gene ID | 134266 |
| Uniprot ID | GRPE2_HUMAN |
| Immunogen Region | 33-225 |
| Immunogen Sequence | STATQRTAGEDCRSEDPPDE LGPPLAERALRVKAVKLEKE VQDLTVRYQRAIADCENIRR RTQRCVEDAKIFGIQSFCKD LVEVADILEKTTECISEESE PEDQKLTLEKVFRGLLLLEA KLKSVFAKHGLEKLTPIGDK YDPHEHELICHVPAGVGVQP GTVALVRQDGYKLHGRTIRL ARVEVAVESQRRL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 33-225 of human GRPEL2 (NP_689620.2). |
Additional Info
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70. |
| Protein Name | Grpe Protein Homolog 2 - MitochondrialMt-Grpe#2 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Grpe Protein Homolog 2 - Mitochondrial antibodyAnti-Mt-Grpe#2 antibodyAnti-GRPEL2 antibody |
Information sourced from Uniprot.org