Anti-GRK3 antibody (1-300) (STJ22535)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADRBK2 (1-300) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GRK3 |
| Gene ID | 157 |
| Uniprot ID | ARBK2_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MADLEAVLADVSYLMAMEKS KATPAARASKRIVLPEPSIR SVMQKYLAERNEITFDKIFN QKIGFLLFKDFCLNEINEAV PQVKFYEEIKEYEKLDNEED RLCRSRQIYDAYIMKELLSC SHPFSKQAVEHVQSHLSKKQ VTSTLFQPYIEEICESLRGD IFQKFMESDKFTRFCQWKNV ELNIHLTMNEFSVHRIIGRG GFGEVYGCRKADTGKMYAMK CLDKKRIKMKQGETLALNE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ADRBK2 (NP_005151.2). |
Additional Info
| Post Translational Modifications | Ubiquitinated. |
| Function | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. |
| Protein Name | G Protein-Coupled Receptor Kinase 3Beta-Adrenergic Receptor Kinase 2Beta-Ark-2 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-8856825 |
| Cellular Localisation | PostsynapsePresynapse |
| Alternative Antibody Names | Anti-G Protein-Coupled Receptor Kinase 3 antibodyAnti-Beta-Adrenergic Receptor Kinase 2 antibodyAnti-Beta-Ark-2 antibodyAnti-GRK3 antibodyAnti-ADRBK2 antibodyAnti-BARK2 antibody |
Information sourced from Uniprot.org