| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GRIP1 (1-1061) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GRIP1 |
| Gene ID: |
23426 |
| Uniprot ID: |
GRIP1_HUMAN |
| Immunogen Region: |
1-1061 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-1061 of human GRIP1 (NP_001171545.1). |
| Immunogen Sequence: |
MIAVSFKCRCQILRRLTKDE SPYTKSASQTKPPDGALAVR RQSIPEEFKGSTVVELMKKE GTTLGLTVSGGIDKDGKPRV SNLRQGGIAARSDQLDVGDY IKAVNGINLAKFRHDEIISL LKNVGERVVLEVEYELPPVS VQGSSVIFRTVEVTLHKEGN TFGFVIRGGAHDDRNKSRPV VITCVRPGGPADREGTIKPG DRLLSVDGIRLLGTTHAEAM SILKQCGQEAALLIEYDVS |
| Function | May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting. |
| Protein Name | Glutamate Receptor-Interacting Protein 1Grip-1 |
| Database Links | Reactome: R-HSA-416993 |
| Cellular Localisation | Cytoplasmic VesiclePerikaryonCell ProjectionDendriteCytoplasmEndomembrane SystemPeripheral Membrane ProteinPostsynaptic Cell MembranePostsynaptic DensityEndoplasmic Reticulum MembraneMembrane-Associated With VesiclesPeri-Golgi Complexes And Endoplasmic ReticulumEnriched In Postsynaptic Plasma Membrane And Postsynaptic Densities |
| Alternative Antibody Names | Anti-Glutamate Receptor-Interacting Protein 1 antibodyAnti-Grip-1 antibodyAnti-GRIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
