| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-G-protein coupled receptor 62 (181-230 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPR62 |
| Gene ID: | 118442 |
| Uniprot ID: | GPR62_HUMAN |
| Immunogen Region: | 181-230 aa |
| Specificity: | GPR62 Polyclonal Antibody detects endogenous levels of GPR62 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human GPR62 at the amino acid range 181-230 |
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 62G-Protein Coupled Receptor Gpcr8Hgpcr8G-Protein Coupled Receptor Kpg_005 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndosome MembraneColocalizes With Arrb2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 62 antibodyAnti-G-Protein Coupled Receptor Gpcr8 antibodyAnti-Hgpcr8 antibodyAnti-G-Protein Coupled Receptor Kpg_005 antibodyAnti-GPR62 antibody |
Information sourced from Uniprot.org