Anti-GPR62 antibody (181-230 aa) (STJ93392)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GPR62 at the amino acid range 181-230
General Information
| Short Description | Rabbit polyclonal anti-G-protein coupled receptor 62 (181-230 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPR62 |
| Gene ID | 118442 |
| Uniprot ID | GPR62_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GPR62 at the amino acid range 181-230 |
| Immunogen Region | 181-230 aa |
| Specificity | GPR62 Polyclonal Antibody detects endogenous levels of GPR62 protein. |
Additional Info
| Function | Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment. Shows a reciprocal modulation of signaling functions with the melatonin receptor MTNR1B most likely through receptor heteromerization. |
| Protein Name | G-Protein Coupled Receptor 62G-Protein Coupled Receptor Gpcr8Hgpcr8G-Protein Coupled Receptor Kpg_005 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndosome MembraneColocalizes With Arrb2 In The Endosome |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor 62 antibodyAnti-G-Protein Coupled Receptor Gpcr8 antibodyAnti-Hgpcr8 antibodyAnti-G-Protein Coupled Receptor Kpg_005 antibodyAnti-GPR62 antibody |
Information sourced from Uniprot.org